雷吉纳德·欧文

Reginald Owen

饰：Sherlock Holmes

黄柳霜

Anna May Wong

饰：Mrs. Pyke

琼·克莱德

June Clyde

饰：Eileen Forrester

Alan Dinehart

饰：Thaddeus Merrydew

约翰·沃伯顿

John Warburton

饰：John Stanford

阿兰·莫布雷

Alan Mowbray

饰：Inspector Lastrade

Warburton Gamble

饰：Dr. John H. Watson

J·M·克里根

J.M. Kerrigan

饰：Jabez Wilson

多丽丝·劳埃德

Doris Lloyd

饰：Mrs. Annabelle Murphy

比利·贝文

Billy Bevan

饰：Will Swallow

Leila Bennett

饰：Daft Dolly

Wyndham Standing

饰：Captain Robin S. Pyke

哈利韦尔·霍布斯

Herbert Halliwell Hobbes

饰：Malcolm Dearing

塞西尔·雷诺兹

Cecil Reynolds

饰：William Baker

Tetsu Komai

饰：Ah Yet

坦普·皮戈特

Tempe Pigott

饰：Mrs. Hudson

霍巴特·卡瓦诺

Hobart Cavanaugh

饰：Innkeeper Thompson (uncredited)

奥拉夫·许滕

Olaf Hytten

饰：Merrydew's Butler (uncredited)